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KMID : 0364020040370070559
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Korean Journal of Thoracic and Cardiovascular Surgery
2004 Volume.37 No. 7 p.559 ~ p.569
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Long-term Results after 1,144 CarboMedics Mechanical Valve Implantation
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Kang Chang-Hyun
Kim Kyung-Hwan
Kim Ki-Bong
Ahn Hyuk
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Abstract
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Background: The CarboMedics mechanical valve has been reported to show acceptable valve-related complication rates. The aim of this study is to evaluate our clinical experience with the CarboMedics valve.
Material and Method: Between August 1988 and September 1999, we implanted 1,144 CarboMedics valves in 850 patients
(aortic 179; mitral 385; double-valve 234; tricuspid 52). The mean age was 44.5±12.5 years. Follow-up was completed in 95.2% and median follow-up period was 7.9 years (6753 patient-years).
Result: The overall hospital mortality rate was 3.4% and the mortality rate for each group was 1.7% for aortic group, 2.6% for mitral group, 4.7% for double-valve group, and 9.6% for tricuspid group. Tricuspid group showed significantly higher mortality rate than aortic and mitral group (p＜0.05). The actuarial survival at 10 years was 87.1±2.6%, 88.9±1.7%, 82.4±
2.9%, and 77.5±7.0% for aortic, mitral, double, and tricuspid valve group, respectively. Age and tricuspid valve replacement were significant risk factors for long-term survival in multivariate analysis (p＜0.05). Freedom from valve thrombosis at 10 years was 99.4±0.6%, 98.2±0.8%, 99.2±0.8%, and 87.6±0.5% for aortic, mitral, double and tricuspid valve group. Tricuspid valve group showed significantly higher rate of valve thrombosis (p＜0.05).
Conclusion: Long-term results of our experience demonstrated that CarboMedics valve showed acceptable incidence of valve-related complications. However, tricuspid valve replacement showed higher rate of early mortality and valve thrombosis than other valve replacement groups.
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KEYWORD
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Heart valve, mechanical, Heart valve prosthesis, Survival , Complication
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